All articles

Nutrition & Metabolism

Ultra-Processed Foods:
What They Are, Why They Matter and How to Read a Label

Aevum Protocol8 min read

Ultra-processed foods (UPFs) are industrial products made mostly from refined ingredients and additives, such as soft drinks, packaged snacks, biscuits, instant noodles, sweetened breakfast cereals, processed meats and many ready meals. They're cheap, convenient and designed to be very tasty, and they now make up a large share of diets around the world. Evidence of harm has grown rapidly. In a US National Institutes of Health trial, people offered an ultra-processed diet ate about 500 more calories a day and gained 0.9 kg in two weeks, compared with an unprocessed diet with meals matched for calories, sugar, fat and fibre. A 2024 BMJ review of 45 meta-analyses covering almost 10 million people found convincing evidence linking high UPF intake to about a 50% higher risk of death from cardiovascular disease, a 48-53% higher risk of anxiety and common mental disorders, and a 12% higher risk of type 2 diabetes, plus a 21% higher risk of death from any cause. Not every processed food is harmful, and the evidence is mostly observational, but eating mostly fresh and minimally processed food is a sensible goal. This article explains how to recognise UPFs, why they matter and how to read labels, including Sri Lanka's colour-coded labels.

Key numbers

FindingDetail
UPF diet trial (20 adults, NIH, 2 weeks per diet)About 500 more calories a day; 0.9 kg gained vs 0.9 kg lost on the unprocessed diet
UPFs and health (45 meta-analyses, almost 10 million people)Convincing evidence for ~50% higher cardiovascular death, 48-53% higher anxiety and common mental disorders, 12% higher type 2 diabetes
UPFs and death from any cause (same review)21% higher risk (highly suggestive evidence)
UPFs and depression (same review)22% higher risk
Sri Lanka's colour-coded labelsSugar in drinks from 2016; sugar, salt and fat in solid foods from January 2020

What makes a food "ultra-processed"

The NOVA system, the most widely used classification, sorts foods into four groups by how much they've been processed:

A useful rule of thumb: if the ingredient list is long and includes things you wouldn't find in a home kitchen, such as glucose syrup, hydrogenated oil, flavour enhancers, emulsifiers or colours, it's probably ultra-processed.

Common examples include soft drinks and energy drinks, packaged snacks and chips, biscuits and cakes, instant noodles, sweetened breakfast cereals, flavoured yoghurts, sausages, meatballs and other processed meats, and many fast foods.

Diagram, from whole foods to ultra-processed: the four NOVA groups are 1, unprocessed or minimally processed foods such as vegetables, fruit, fish, eggs, rice and dhal; 2, culinary ingredients such as oils, salt and sugar; 3, processed foods such as canned fish, cheese and pickles; and 4, ultra-processed foods such as soft drinks, packaged snacks, biscuits, instant noodles and sausages

Why ultra-processed foods matter

They make us eat more. In 2019, US National Institutes of Health researchers ran the first randomised trial of UPFs. Twenty adults lived at the research centre for a month, eating an ultra-processed diet for two weeks and an unprocessed diet for two weeks, in random order. The meals offered were matched for calories, sugar, fibre, fat and carbohydrate, and participants could eat as much as they liked. On the ultra-processed diet, they ate about 500 more calories a day, ate faster and gained 0.9 kg; on the unprocessed diet, they lost a similar amount. The researchers concluded that UPFs cause overeating and weight gain.

Stat tiles, ultra-processed food makes us eat more: about 500 extra calories a day on the ultra-processed diet, 0.9 kg gained in two weeks on ultra-processed food and 0.9 kg lost in two weeks on unprocessed food, with meals matched for calories, sugar, fat and fibre (Hall et al., Cell Metabolism, 2019, 20 adults)

They're linked to many chronic diseases. A 2024 umbrella review in The BMJ combined 45 meta-analyses, including almost 10 million participants, and found that higher UPF intake was linked to 32 harmful health outcomes. The evidence was rated as convincing for:

There was highly suggestive evidence for a 21% higher risk of death from any cause, a 40-66% higher risk of death from heart disease, obesity, sleep problems and a 22% higher risk of depression. These are mostly observational studies, so they show association rather than proof, but the consistency across many outcomes is striking.

Horizontal bar chart, ultra-processed food and health, higher risk with high vs low intake: death from cardiovascular disease 50%, anxiety and common mental disorders 48%, depression 22%, death from any cause 21% and type 2 diabetes 12% (Lane et al., BMJ, 2024, 45 meta-analyses, almost 10 million people)

Why they might be harmful.

Risk factor table: ultra-processed foods and health

FactorEffectModifiable?Evidence strength
Sugary drinks and energy drinksExcess sugar and calories; linked to weight gain and diabetesYesStrong
Processed meats (sausages, ham, bacon)Linked to bowel cancer and heart diseaseYesStrong
Packaged snacks, biscuits and sweetsHigh in sugar, salt and unhealthy fat; easy to overeatYesModerate
Instant noodles and ready mealsHigh in salt and refined starch, low in fibreYesModerate
Sweetened cereals and flavoured yoghurtsHidden sugars; marketed as healthyYesModerate
Eating quickly and while distractedEncourages overeatingYesModerate
Low cost and easy availability of UPFsDrives higher intakePartlyStrong

What you can actually change

1. Swap your biggest sources first. Most people get much of their UPF intake from a few foods. Replace sugary drinks with water, plain tea or coffee, and swap packaged snacks for fruit, nuts, roasted chickpeas or plain curd.

2. Cook simple meals at home. Rice, dhal, vegetables, fish and eggs prepared at home are minimally processed. Batch cooking helps on busy days.

3. Choose the less-processed version. Plain curd instead of flavoured yoghurt, oats instead of sweetened cereals, fresh fish or chicken instead of sausages or nuggets, and wholemeal bread with a short ingredient list.

4. Read the label.

5. Don't aim for perfection. Some processed foods, such as canned fish, plain yoghurt, frozen vegetables and wholemeal bread, are convenient and healthy. The goal is to make fresh and minimally processed foods the base of your diet.

Recommendations

Practical notes

Ultra-processed foods are designed to be convenient and hard to stop eating. A controlled trial shows that they cause people to eat more and gain weight, and large reviews link them to heart disease, diabetes, mental health problems and earlier death. You don't need to eliminate them completely, but making fresh and minimally processed foods the core of your diet, cooking simple meals and reading labels are some of the most effective steps you can take for long-term health.

References
  1. Hall KD, et al. Ultra-processed diets cause excess calorie intake and weight gain: an inpatient randomized controlled trial of ad libitum food intake. Cell Metabolism, 2019;30(1):67-77.
  2. Lane MM, et al. Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ, 2024;384:e077310.
  3. Monteiro CA, et al. Ultra-processed foods: what they are and how to identify them. Public Health Nutrition, 2019;22(5):936-941.
  4. Ministry of Health, Sri Lanka. Food (Colour Coding for Sugar, Salt and Fat) Regulations, 2019. Reported by Food Compliance International.

Free longevity assessment

How much of what you ate today
came out of a packet?

Take the free Aevum Protocol assessment to see how your nutrition & metabolism and 6 other longevity domains are performing — and get a personalised 90-day plan.

Take the free assessment